- Is a powerful probiotic
- Helps to control cholesterol levels in the body
- Improves immunity
- Helps in the treatment of celiac disease
- Can control the glucose level in the blood
- Can eliminate H. pylori and prevents against peptic ulcers
- Eliminates bad bacteria from the mouth
- Improves the digestive system
- Beneficial for control of inflammatory disorders
- Effective against inflammatory bowel syndrome
- Has antitumor activity
B. lactis is a widely used probiotic and is considered a champion among the “good bacteria”. It has been reclassified by Masco et al. (2004) and has been found to be related to Bifidobacterium animalis at the sup specie level, B. animalis subsp. Lactis. B. lactis is a common inhabitant of the colon and intestines of humans and animals. The use of B. lactis in diets has shown beneficial effects in the treatment of various gluten-based enteropathies. Celiac disease is an autoimmune disorder which is aggravated by the consumption of gluten-based food products.
According to Lindfors et al. (2008), the oral intake of B. lactis based-probiotics protects the intestinal cells from the toxic effects of gluten enteropathies and inflammatory reactions. The regular consumption of B. lactis aids in controlling abnormal weight gain and diabetes in animal models. Stenman et al. (2014) administered a probiotic based on Bifidobacterium animalis ssp. Lactis 420 to mice, which showed positive results in controlling weight gain due to a high-fat diet and diabetes. Tolerance to glucose was found to be improved in test animals that were fed B. lactis.
In a study carried out in 2000, the antimicrobial effects of B. lactis were determined. It was reported that regular consumption of B. lactis probiotics aids in preventing food-borne disease caused by Salmonella and E.coli. In another study, it was proposed that consumption of B. lactis-fortified milk led to an improvement in the immune system, with individuals showing better resistance to flu, infections, inflammatory conditions, and general sicknesses (Lomax and Calder, 2009). B. lactis has been reported to control the level of cholesterol in the body as well. Jungersen et al. (2014) found that the consumption of B. lactis probiotics provides protection against respiratory disorders.
The colonization of the gastrointestinal tract by B. lactis and the production of antimicrobial compounds inhibits the growth of harmful bacteria, including clostridia and enterobacteria (Mohan et al., 2006). B. lactis is used to relieve the symptoms of lactose intolerance and helps in the digestion and assimilation of lactose-containing compounds. It has proven beneficial in the treatment of peptic ulcers and eases the symptoms of inflammatory bowel syndrome (IBS). These symptoms include bloating, abdominal discomfort, fatigue, and malnutrition. B. lactis has proven to be the probiotic of choice for improving the microflora of the mouth by aiding in the prevention of mouth cavities formed by harmful bacteria.
B. lactis has shown to have antitumor activity and many researches support this probiotic’s feature. Le Leu et al. (2010) reported that B. lactis has the ability to utilize resistant starch and upregulate apoptotic responses against colorectal cancerous cells. B. lactis can improve immunity by enhancing the activity of natural killer cells that destroy tumors and the phagocytic activity of polymorphonuclear leukocytes, which fight infections in the body. The consumption of B. lactis-fortified milk greatly strengthens the immune system and helps in the eradication of and in the prevention against different diseases (Chang et al., 2000).
Jungersen, M., Wind, A., Johansen, E. et al. (2014). The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12. Microorganisms, 2, 92-110
Le Leu, R.K., Hu, Y., Brown, I.L. & Woodman, R.J. (2010). Synbiotic intervention of Bifidobacterium lactis and resistant starch protects against colorectal cancer development in rats. Carcinogenesis, 31(2), 246-51
Lindfors, K., Blomqvist, T., Juuti-Uusitalo, K., Stenman, S., Venäläinen, J., Mäki, M. & Kaukinen, K. (2008). Live probiotic Bifidobacterium lactis bacteria inhibit the toxic effects induced by wheat gliadin in epithelial cell culture. Clin Exp Immunol. 2008 Jun; 152(3): 552–558
Lomax, A.R., Calder, P.C. (2009). Probiotics, immune function, infection and inflammation: a review of the evidence from studies conducted in humans. Curr Pharm Des. 15(13), 1428-518.
Stenman, L. K., Waget, A., Garret, C., Klopp, P., Burcelin, R. & Lahtinen, S. (2014). Potential probiotic Bifidobacterium animalis ssp. lactis 420 prevents weight gain and glucose intolerance in diet-induced obese mice. Benef Microbes, 5(4), 437-45